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Archaeal transcription factor B
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Archaeal transcription factor B : ウィキペディア英語版
Archaeal transcription factor B
Archaeal transcription factor B (ATFB or TFB) (homologous to eukaryotic TFIIB) is a polypeptide important in archaeal transcription.
==Structure==
TFB is comprised an amino-terminal region (TFBN) and a larger carboxyl-terminal region (TFBC).
TFBN is approximately one third of the protein and contains both a B-finger motif (homologous to the TFIIB B-finger) and a zinc-finger motif.
TFBC is folded into a globulus which binds to the TATA binding protein (TBP) and to TFB-recognition elements (BRE) upstream of the TATA box. These bindings are important for transcription polarity.〔http://www.pnas.org/content/96/24/13662.full〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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